Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers

Zwirner, J.; Safavi, S.; Scholze, M.; Li, K. C.; Waddell, J. N.; Busse, B.; Ondruschka, B.; Hammer, N.

doi:10.1038/s41598-020-80548-y

Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers (bibtex)

by J. Zwirner, S. Safavi, M. Scholze, K. C. Li, J. N. Waddell, B. Busse, B. Ondruschka, N. Hammer

Abstract:

The site-dependent load-deformation behavior of the human neurocranium and the load dissipation within the three-layered composite is not well understood. This study mechanically investigated 257 human frontal, temporal, parietal and occipital neurocranial bone samples at an age range of 2 to 94 years, using three-point bending tests. Samples were tested as full-thickness three-layered composites, as well as separated with both diploë attached and removed. Right temporal samples were the thinnest samples of all tested regions (median < 5 mm; p < 0.001) and withstood lowest failure loads (median < 762 N; p < 0.001). Outer tables were thicker and showed higher failure loads (median 2.4 mm; median 264 N) than inner tables (median 1.7 mm, p < 0.001; median 132 N, p = 0.003). The presence of diploë attached to outer and inner tables led to a significant reduction in bending strength (with diploë: median < 60 MPa; without diploë: median > 90 MPa, p < 0.001). Composites (r = 0.243, p = 0.011) and inner tables with attached diploë (r = 0.214, p = 0.032) revealed positive correlations between sample thickness and age. The three-layered composite is four times more load-resistant compared to the outer table and eight times more compared to the inner table.

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Reference:

Zwirner, J., Safavi, S., Scholze, M., Li, K. C., Waddell, J. N., Busse, B., Ondruschka, B., Hammer, N.: Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers, Scientific Reports 11, 3721, 2021.

Bibtex Entry:

@Article{Zwirner2021a,
  author   = {Zwirner, J. and Safavi, S. and Scholze, M. and Li, K. C. and Waddell, J. N. and Busse, B. and Ondruschka, B. and Hammer, N.},
  journal  = {Scientific Reports},
  title    = {Topographical mapping of the mechanical characteristics of the human neurocranium considering the role of individual layers},
  year     = {2021},
  issn     = {2045-2322},
  month    = feb,
  number   = {1},
  pages    = {3721},
  volume   = {11},
  abstract = {The site-dependent load-deformation behavior of the human neurocranium and the load dissipation within the three-layered composite is not well understood. This study mechanically investigated 257 human frontal, temporal, parietal and occipital neurocranial bone samples at an age range of 2 to 94 years, using three-point bending tests. Samples were tested as full-thickness three-layered composites, as well as separated with both diploë attached and removed. Right temporal samples were the thinnest samples of all tested regions (median < 5 mm; p < 0.001) and withstood lowest failure loads (median < 762 N; p < 0.001). Outer tables were thicker and showed higher failure loads (median 2.4 mm; median 264 N) than inner tables (median 1.7 mm, p < 0.001; median 132 N, p = 0.003). The presence of diploë attached to outer and inner tables led to a significant reduction in bending strength (with diploë: median < 60 MPa; without diploë: median > 90 MPa, p < 0.001). Composites (r = 0.243, p = 0.011) and inner tables with attached diploë (r = 0.214, p = 0.032) revealed positive correlations between sample thickness and age. The three-layered composite is four times more load-resistant compared to the outer table and eight times more compared to the inner table.},
  doi      = {10.1038/s41598-020-80548-y},
  refid    = {Zwirner2021},
  url      = {https://doi.org/10.1038/s41598-020-80548-y},
}